![]() Expression Biased expression in limb E14.5 (RPKM 593.4), CNS E18 (RPKM 350. The lncRNA Rian may serve as a potential target for novel treatment in patients with ischemic stroke. findings showed that the Rian/miR-144-3p/GATA3 axis is an essential signaling in cerebral I/R injury. Orthologous to human MEG8 (maternally expressed 8, small nucleolar RNA host gene). Meg8 suppresses hepatic stellate cells activation and hepatocyte epithelial-mesenchymal transition through inhibiting the Notch pathway. ![]() Is expressed in several structures, including adrenal gland central nervous system gut metanephros and sensory organ. Full Name RNA imprinted and accumulated in nucleus provided by MGI Primary source MGI:MGI:1922995 See related AllianceGenome:MGI:1922995 Gene type ncRNA RefSeq status PREDICTED Organism Mus musculus Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus Also known as Meg8 5530401N18Rik C130089L09Rik Summary Acts upstream of or within several processes, including epithelial to mesenchymal transition negative regulation of Notch signaling pathway and negative regulation of hepatic stellate cell activation.
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